Workshops

ECCB10 will feature two one-day workshop sessions on Sunday, September 26, 2010:

WORKSHOP 1: LEARNING FROM PERTURBATION EFFECTS

Reverse engineering of biological networks is a key for the understanding of biological systems and for identifying new drug targets. Perturbation techniques, like target specific inhibitors and RNA interference, open tremendous possibilities to detect so far unknown interdependencies from, possibly multidimensional, effects. At the same time computational methods being able to derive network hypotheses from such complex data play a crucial role. This workshop aims to bring together computational scientists working with various approaches for this challenging task. The goal is to give an overview over different computational methods in the field and to strengthen and initiate new cooperations.

WORKSHOP 2: ANNOTATION, INTERPRETATION, AND MANAGEMENT OF MUTATIONS (AIMM)

This workshop will showcase the state of the art in extraction and reuse of genotype-phenotype information. Annotation of mutations with their impact on phenotypic expression is crucial to understanding genetic mechanisms involved in phenotypic processes and ultimately in complex diseases. Managing this knowledge is key to generating novel hypotheses. Despite the existence of literature and databases describing impacts of mutations, association studies fail to deliver linkage to phenotypes which is the most important contemporary research interest. Extraction of such information from scientific literature is a promising research field and existing solutions are ready to be deployed as services and as semantic web services.